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主要更新与大生物医药领域的一些东西……
Optical coherence tomography (OCT) is susceptible to the coherent noise, which is the speckle noise that deteriorates contrast and the detail structural information of OCT images, thus imposing significant limitations on the diagnostic capability of OCT. In this paper, we propose a novel OCT image denoising method by using an end-to-end deep learning network with a perceptually-sensitive loss function. The method has been validated on OCT images acquired from healthy volunteers’ eyes. The label images for training and evaluating OCT denoising deep learning models are images generated by averaging 50 frames of respective registered B-scans acquired from a region with scans occurring in one direction. The results showed that the new approach can outperform other related denoising methods on the aspects of preserving detail structure information of retinal layers and improving the perceptual metrics in the human visual perception.
一作文章：
Bin Qiu#, Zhiyu Huang, Xi Liu, Xiangxi Meng, Yunfei You, Gangjun Liu, Kun Yang, Andreas Maier, Qiushi Ren, Yanye Lu*, “Noise reduction in optical coherence tomography images using a deep neural network with perceptually-sensitive loss function,” Biomed Opt Express 11, 817-830 (2020). 论文链接
Bin Qiu#, Yunfei You, Zhiyu Huang, Xiangxi Meng, Zhe Jiang, Chuanqing Zhou, Gangjun Liu, Kun Yang, Qiushi Ren, Yanye Lu*, “N2NSR-OCT: Simultaneous Denoising and Super-resolution in Optical Coherence Tomography Images using Semi-supervised Deep Learning,” J Biophotonics (2020) (Accepted). 论文链接
其他作者序列文章：
- Zhe Jiang, Zhiyu Huang, Bin Qiu, Xiangxi Meng, Yunfei You, Xi Liu, Gangjun Liu, Chuangqing Zhou, Kun Yang, Andreas Maier, Qiushi Ren, and Yanye Lu, "Comparative study of deep learning models for optical coherence tomography angiography," Biomed. Opt. Express 11, 1580-1597 (2020) 论文链接